The Landes Research Group at Rice University


The Landes Research Group develops new spectroscopic tools to image chemical dynamics at interfaces at the limit of a single event. Using this super-resolved chemical knowledge, we create new models to understand and predict macroscale processes like protein separation and photocatalysis.


 

Ensemble vs. Single Molecule

A wide range of biological and materials processes rely on nanoscale interfacial dynamics. Single molecule methods allow us to identify the chemical complexity of these interactions by revealing the underlying populations that form the ensemble measurement. In doing so, we can identify and tune the rare chemical populations that play a crucial role in reactivity.

Towards Predictive Separations

The cost of bringing a new protein based therapeutic to market averages ~$2.6 billion dollars, of which 50% can be dedicated to isolating and purifying the active compound. A primary contributor to the cost is the empirical optimization of chromatographic separation. Our lab seeks to understand separations from the scale of individual analytes, with a goal to create a new predictive model of chromatography to eliminate the need for costly empirical methods.

 

Breaking the Abbe-Diffraction Limit

The Abbe diffraction limit sets a lower bound of a few hundred nanometers for the size of objects we can observe with traditional optical microscopy. This limit is defined by light’s wavelength. Our lab develops new mathematical methods to break the Abbe diffraction limit and achieve spatial resolutions of just a few nanometers and time resolutions faster than traditional cameras frame times.

Congratulations.   03/31/2023

Jagriti ChatterjeeEmil GillettJiamu Lin

Congratulations Jagriti Chatterjee, Emil Gillett and Jiamu Lin on passing your Qualifying Exam. Good luck on the years to come!

New Postdoctoral Scholar   11/10/2022

Jeladhara Shobhanan

We are happy to welcome our new Postdoctoral Researcher Jeladhara Shobhanan We look forward to your accomplishments in this group!

Welcome!   09/15/2022

Dr. Zhe QiangSara Valdez

The Landes Research Group welcomes our Visting Scientist Dr. Zhe Qiang (Asst. Prof at University of Southern Mississippi) and Visiting Student , Sara Valdez We are glad you are here!

Thank you Summer Interns   08/07/2022

Dr. Shawna LeeJohn FergusonMalaysia Moses

Thank you Dr. Shawna Lee , John Ferguson and Malaysia Moses for joining us this summer! We had a great time having you all and best wishes for your future endeavors

Predictive Separations

Predictive Separations

Spectro-electrochemistry

Spectro-electrochemistry

Protein Dynamics at Interfaces

Protein Dynamics at Interfaces

Imaging and Signal Processing

Imaging and Signal Processing

Single-Molecule Spectroscopy

Single-Molecule Spectroscopy

Gross, N.,Madadi, M.,Ostovar,B.,Dongare, P. D.,McCarthy,L.A.,Chiang, W.Y.,Chang, W.S.,Halas,N.J.,Landes, C. F.,Sader, J.E., Link,S., "Strong Substrate Binding Modulates the Acoustic Quality Factors in Gold Nanodisks" J. Phys. Chem. C 2023, 127, 10, 5054–5066 (2023)

Al-Zubeidi, A.,Ostovar, B., Carlin, C.C., Cam Li,B., Lee, S.A., Chiayng,W.Y., Gross, N., Dutta, S., Misiura, A., Searles, E.K., Chakraborty, A., Roberts, S.T., Dionne, J.A., Rossky, P.J., Landes, C. F., Link,S., "Mechanism for plasmon-generated solvated electrons" Proceedings of the National Academy of Sciences of the United States of America. , 2023, Vol.120(3), p.e2217035120 (2023)

Searles, E.K., Gomez, E., Lee,S.A., Ostovar, B., Link, S., Landes, C. F., "Single-Particle Photoluminescence and Dark-Field Scattering during Charge Density Tuning" J. Phys. Chem. Lett. 2023, 14, 2, 318–325 (2023)

Lee A, S., Ostovar, B.,Landes, C. F., Link S., "Spectroscopic signatures of plasmon-induced charge transfer in gold nanorods" J. Chem. Phys. 156, 064702 (2022)

Warning A, L., Miandashti, A R., Misiura, A., Landes, C. F., Link S., "Naturally Occurring Proteins Direct Chiral Nanorod Aggregation" J. Phys. Chem. C 2022

Rice University
Chemistry Department
Smalley-Curl Institute
ECE Department
LaNSIR
IBB
The Landes Research Group at Rice University in Houston, Texas

The Landes Research Group at Rice University


The Landes Research Group develops new spectroscopic tools to image chemical dynamics at interfaces at the limit of a single event. Using this super-resolved chemical knowledge, we create new models to understand and predict macroscale processes like protein separation and photocatalysis.


 

Ensemble vs. Single Molecule

A wide range of biological and materials processes rely on nanoscale interfacial dynamics. Single molecule methods allow us to identify the chemical complexity of these interactions by revealing the underlying populations that form the ensemble measurement. In doing so, we can identify and tune the rare chemical populations that play a crucial role in reactivity.

Towards Predictive Separations

The cost of bringing a new protein based therapeutic to market averages ~$2.6 billion dollars, of which 50% can be dedicated to isolating and purifying the active compound. A primary contributor to the cost is the empirical optimization of chromatographic separation. Our lab seeks to understand separations from the scale of individual analytes, with a goal to create a new predictive model of chromatography to eliminate the need for costly empirical methods.

 

Breaking the Abbe-Diffraction Limit

The Abbe diffraction limit sets a lower bound of a few hundred nanometers for the size of objects we can observe with traditional optical microscopy. This limit is defined by light’s wavelength. Our lab develops new mathematical methods to break the Abbe diffraction limit and achieve spatial resolutions of just a few nanometers and time resolutions faster than traditional cameras frame times.

Ph.D.   06/17/2021

Charlotte Flatebo

Congratulations to Charlotte Flatebo for successfully completing her Ph.D thesis defense! We will miss you and wish you the best luck at UCSB!

Quals Passed   06/09/2021

Dongyu Fan

Congratulations to Dongyu Fan on passing her Qualifying Exam! We look forward to more awesome work from you in the future!

Ph.D.   03/31/2021

Logan Bishop

Congratulations to Logan Bishop for successfully defending his Ph.D! Good luck at 3M!

Ph.D.   03/11/2021

Rashad Baiyasi

Congratulations to Rashad Baiyasi for passing his thesis defense. Good luck with the coming future!

Predictive Separations

Predictive Separations

Spectro-electrochemistry

Spectro-electrochemistry

Protein Dynamics at Interfaces

Protein Dynamics at Interfaces

Imaging and Signal Processing

Imaging and Signal Processing

Single-Molecule Spectroscopy

Single-Molecule Spectroscopy

Al-Zubeidi, A., Stein, F., Flatebo, C., Rehbock, C., Hosseini Jebeli, S. A., Landes, C. F., Barcikowski, S., Link, S.,, "Single-Particle Hyperspectral Imaging Reveals Kinetics of Silver Ion Leaching from Alloy Nanoparticles" ACS Nano 2021

Baiyasi, R., Goldwyn, H. J., McCarthy, L. A., West, C. A., Hosseini Jebeli, S. A., Masiello, D. J., Link, S., Landes, C. F., "Coupled-Dipole Modeling and Experimental Characterization of Geometry-Dependent Trochoidal Dichroism in Nanorod Trimers" ACS Photonics 2021, 8, 4, 1159–1168

Heiderscheit, T. S., Oikawa, S., Sanders, S., Minamimoto, H., Searles, E. K., Landes, C. F., Murakoshi, K., Manjavacas, A., Link, S., "Tuning Electrogenerated Chemiluminescence Intensity Enhancement Using Hexagonal Lattice Arrays of Gold Nanodisks" J. Phys. Chem. Lett. 2021, 2516-2522

Collins, S. S. E., Searles, E. K., Tauzin, L. J., Lou, M., Bursi, L., Liu, Y., Song, J., Flatebo, C., Baiyasi, R., Cai, Y. Y., Foerster, B., Lian, T., Nordlander, P., Link, S., Landes, C. F., "Plasmon Energy Transfer in Hybrid Nanoantennas" ACS Nano 2020

Calabrase, W., Bishop, L. D. C., Dutta, C., Misiura, A., Landes, C. F., Kisley, L., "Transforming Separation Science with Single-Molecule Methods" Anal. Chem. 2020, 92, 20, 13622-13629

Rice University
Chemistry Department
Smalley-Curl Institute
ECE Department
LaNSIR
IBB
The Landes Research Group at Rice University in Houston, Texas

The Landes Research Group at Rice University


The Landes Research Group develops new spectroscopic tools to image chemical dynamics at interfaces at the limit of a single event. Using this super-resolved chemical knowledge, we create new models to understand and predict macroscale processes like protein separation and photocatalysis.


 

Ensemble vs. Single Molecule

A wide range of biological and materials processes rely on nanoscale interfacial dynamics. Single molecule methods allow us to identify the chemical complexity of these interactions by revealing the underlying populations that form the ensemble measurement. In doing so, we can identify and tune the rare chemical populations that play a crucial role in reactivity.

Towards Predictive Separations

The cost of bringing a new protein based therapeutic to market averages ~$2.6 billion dollars, of which 50% can be dedicated to isolating and purifying the active compound. A primary contributor to the cost is the empirical optimization of chromatographic separation. Our lab seeks to understand separations from the scale of individual analytes, with a goal to create a new predictive model of chromatography to eliminate the need for costly empirical methods.

 

Breaking the Abbe-Diffraction Limit

The Abbe diffraction limit sets a lower bound of a few hundred nanometers for the size of objects we can observe with traditional optical microscopy. This limit is defined by light’s wavelength. Our lab develops new mathematical methods to break the Abbe diffraction limit and achieve spatial resolutions of just a few nanometers and time resolutions faster than traditional cameras frame times.

Departmental Achievement Awards   08/06/2022

Jagriti ChatterjeeZhenyang Jia

Congratulations to JagritiChatterjee, Zhenyang Jia for winning the Gold and Silver Awards respectively at 9th SCI colloquium poster session.Keep up the good work!

Congratulations.   06/20/2023

Zhenyang Jia

Congratulations Zhenyang Jia on passing your Qualifying exam! Best wishes for your future work!

Departmental Achievement Awards   04/28/2023

Selena

Congratulations to Selena Zermeño for winning this year's School of Natural Sciences winner of the Staff Service Award!!!, You deserve every success!

Congratulations   04/04/2023

Emily Searles

Congratulations, Emily Searles, on your Ph.D. defense. We will miss you ! Good luck with the coming future!

Predictive Separations

Predictive Separations

Spectro-electrochemistry

Spectro-electrochemistry

Protein Dynamics at Interfaces

Protein Dynamics at Interfaces

Imaging and Signal Processing

Imaging and Signal Processing

Single-Molecule Spectroscopy

Single-Molecule Spectroscopy

Gross, N.,Kuhs, C.T, Ostovar,B.,Chiang, W.Y., Wilson, K.S., Volek,T.S., Faitz,Z.M., Carlin, C.C., Dionne, J.A., Zanni, M.T., Gruebele,M., Roberts,S.T., Link,S.,Landes, C. F., "Progress and Prospects in Optical Ultrafast Microscopy in the Visible Spectral Region: Transient Absorption and Two Dimensional Microscopy " J. Phys. Chem. C 2023, 127, 30, 14557–14586

Duan, H., Jia,Z., Liaqat, M. ,Mellor, M.D., Tan,H., Nieh, M.P., Lin, Y., Link, S., Landes, C. F., He,J., "Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization" ACS Nano 2023 (2023)

Fan, D.,Bajgiran,R.S.,Samghabadi,S.F. ,Dutta, C., Gillett,E., Rossky, P.J., Conrad, J.C., Marciel, B.A., Landes, C. F., "Imaging Heterogeneous 3D Dynamics of Individual Solutes in a Polyelectrolyte Brush" Langmuir 2023, 39, 24, 8532–8539 (2023)

Al-Zubeidi, A.,Wang,Y.,Lin,J.,Flatebo, C., Landes C. F., Ren, H., Link, S., "d-Band Holes React at the Tips of Gold Nanorods" J. Phys. Chem. Lett. 2023, 14, 23, 5297–5304 (2023)

Wallum,A.,Liu,Z.,Lee,J.,Chatterjee, S., Tauzin,L., Barr, C.D., Brown,A., Landes, C. F., Nicely, A.L., Gruebele, M., "An Instrument Assembly and Data Science Lab for Early Undergraduate Education" J. Chem. Educ. 2023 (2023)

Lee, S.A.,Kuhs, C.T., Searles,E.K.,Everitt, H.O., Link,S., Landes, C. F., "d-Band Hole Dynamics in Gold Nanoparticles Measured with Time-Resolved Emission Upconversion Microscopy" Nano Lett. 2023, 23, 8, 3501–3506 (2023)

Rice University
Chemistry Department
Smalley-Curl Institute
ECE Department
LaNSIR
IBB