Research Areas

Quantifying heterogeneous structure-function relationships one molecule at a time presents challenges for theory, experiment, and data analysis. We must develop new methods to collect, process, and understand super-resolved spectroscopic data to respond to the challenges of today's scientific problems. As such, our research focuses on three linked objectives:

  • Develop new spectroscopic data acquisition and analysis methods to image dynamics at nanoscale interfaces
  • Define testable hypotheses for protein separations by combining super-resolved protein adsorption and a stochastic theory of ion-exchange chromatography
  • Design methods to control photocatalysis at nanoparticle interfaces with the ultimate goal of controlling single electron transfer
Predictive Separations

Predictive Separations

Spectro-electrochemistry

Spectro-electrochemistry

Protein Dynamics at Interfaces

Protein Dynamics at Interfaces

Imaging and Signal Processing

Imaging and Signal Processing

Single-Molecule Spectroscopy

Single-Molecule Spectroscopy

Moringo, N.A., Bishop, L.D.C., Shen, H., Misiura, A., Carrejo, N.C., Baiyasi, R., Wang, W., Ye, F., Robinson, J.T., Landes C.F., "A mechanistic examination of salting out in protein-polymer membrane interactions PNAS 2019, 116(46) 22938-22945.

Zhang, Q., Hernandez, T., Smith, K.W., Jebeli, S.A.H., Dai, A.X., Warning, L., Baiyasi, R., McCarthy, L.A., Guo, H., Chen, D-H, Dionne, J.A., Landes C.F., Link, S., "Unraveling the origin of chirality from plasmonic nanoparticle-protein complexes Science 2019, 365, 6460, 1475-1478

Cai, Y., Collins, S.S.E., Gallagher, M.J., Bhattacharjee, U., Zhang, R., Chow, T.H., Ahmadivand, A., Ostovar, B., Al-Zubeidi, A., Wnag, Jianfang, Nordlander, P., Landes, C.F., Link, S., "Single Particle emission spectroscopy resolves d-hole relaxation in copper nanocubes ACS Energy lett. 2019, 4, 10, 2458-2465

Heiderscheit, T.S., Gallagher, M.J., Baiyasi, R., Collins, S.S.E., Jebeli, S.A.H., Scarabelli, L., Zl-Zubeidi, A., Flatebo, C., Chang, W-S., Landes, C.F., Link, S., "Nanoelectrode-emitter spectral overlap amplifies surface enhanced electrogenerated chemiluminescence J. Chem. Phys. 151, 144712 (2019)

Flatebo, C., Collins, S.S.E., Hoener, B.S., Cai, Y-Y., Link, S., Landes, C.F., "Electrodissolution Inhibition of Gold Nanorods with Oxoanions J. Phys. Chem. C, 2019

Baiyasi, R, Jebeli, S.A.H., Zhang, Q., Su, L.,Hofkens, J., Uji-i, H., Link, S., Landes, C.F., "PSF Distortion in Dye-Plasmonic Nanomaterial Interactions: Friend or Foe? ACS Photonics 2019, 6(3), pp. 699-708

Wang, W., Ye, F., Shen, H., Moringo, N.A., Dutta, C., Robinson, J.T., Landes, C.F., "Generalized method to design phase masks for 3D super-resolution microscopy Opt. Express 2019, 27(3), pp. 3799-3816

Chatterjee, S., A., Carina, Nurik, C.E., Carrejo, N.C., Dutta, C., Jayaraman, V., Landes, C.F., "Phosphorylation Induces Conformational Rigidity at the C-Terminal Domain of AMPA Receptors J. Phys. Chem. B 2019

Rice University
Chemistry Department
Smalley-Curl Institute
ECE Department
LaNSIR
IBB
NDSEG
NSF
NIH
Rice
Welch