The Landes Research Group at Rice University


The Landes Research Group develops new spectroscopic tools to image chemical dynamics at interfaces at the limit of a single event. Using this super-resolved chemical knowledge, we create new models to understand and predict macroscale processes like protein separation and photocatalysis.


 

Ensemble vs. Single Molecule

A wide range of biological and materials processes rely on nanoscale interfacial dynamics. Single molecule methods allow us to identify the chemical complexity of these interactions by revealing the underlying populations that form the ensemble measurement. In doing so, we can identify and tune the rare chemical populations that play a crucial role in reactivity.

Towards Predictive Separations

The cost of bringing a new protein based therapeutic to market averages ~$2.6 billion dollars, of which 50% can be dedicated to isolating and purifying the active compound. A primary contributor to the cost is the empirical optimization of chromatographic separation. Our lab seeks to understand separations from the scale of individual analytes, with a goal to create a new predictive model of chromatography to eliminate the need for costly empirical methods.

 

Breaking the Abbe-Diffraction Limit

The Abbe diffraction limit sets a lower bound of a few hundred nanometers for the size of objects we can observe with traditional optical microscopy. This limit is defined by light’s wavelength. Our lab develops new mathematical methods to break the Abbe diffraction limit and achieve spatial resolutions of just a few nanometers and time resolutions faster than traditional cameras frame times.

Welcome   05/11/2022

Subhojyoti Chatterjee

The LRG welcomes our new PhD student Zhenyang Jia We look forward to your future successes in this group!

Departmental Achievement Awards   04/26/2022

Annette Jones

Congratulations to AnnetteJones for winning the second position at Chemistry undergrad poster session.Keep up the good work!

New Postdoctoral Scholar   12/01/2021

Subhojyoti Chatterjee

We are happy to welcome our new Postdoctoral Researcher Subhojyoti Chatterjee We look forward to your future successes in this group!

Welcome   11/24/2021

Jagriti ChatterjeeEmil GillettJiamu Lin

The LRG welcomes three new members, Jagriti Chatterjee, Emil Gillett and Jiamu Lin. Good luck on the years to come!

Predictive Separations

Predictive Separations

Spectro-electrochemistry

Spectro-electrochemistry

Protein Dynamics at Interfaces

Protein Dynamics at Interfaces

Imaging and Signal Processing

Imaging and Signal Processing

Single-Molecule Spectroscopy

Single-Molecule Spectroscopy

Lee A, S., Ostovar, B.,Landes, C. F., Link S., "Spectroscopic signatures of plasmon-induced charge transfer in gold nanorods" J. Chem. Phys. 156, 064702 (2022)

Warning A, L., Miandashti, A R., Misiura, A., Landes, C. F., Link S., "Naturally Occurring Proteins Direct Chiral Nanorod Aggregation" J. Phys. Chem. C 2022

Shiratori, K., Bishop, L. D. C., Ostovar, B., Baiyasi, R., Cai, Y., Rossky, P. J., Landes, C. F., Link, S., "Machine-Learned Decision Trees for Predicting Gold Nanorod Sizes from Spectra" J. Phys. Chem. C 2021, 125, 35, 19353–19361

Flatebo, C., Dutta, C., Ostovar, B., Link, S., Landes, C. F., "Heterogeneity and Hysteresis in the Polymer Collapse of Single Core–Shell Stimuli-Responsive Plasmonic Nanohybrids" J. Phys. Chem. C 2021, 125, 33, 18270–18278

Rice University
Chemistry Department
Smalley-Curl Institute
ECE Department
LaNSIR
IBB